Cinnamic acid inhibition cancer cells
WebMar 1, 2024 · Comprehensively, cinnamon and its constituents exhibit the anti-cancer and cancer prevention activities through various mechanisms: (1) anti-proliferation, (2) induction of cell death, (3) anti ... WebMar 23, 2016 · For the inhibition of cancer cell proliferation, the concentration of tCA reaching mM levels was required; however, the study data verified that tCA interfered in histone acetylation via inhibiting HDAC, leading to cancer cell cytotoxicity. In addition, the therapeutic efficacy of tCA has been confirmed. ... Cinnamic acid induces apoptotic cell ...
Cinnamic acid inhibition cancer cells
Did you know?
WebApr 10, 2024 · Cervical carcinoma is one of the most common cancers among women globally. Histone deacetylase inhibitors (HDACIs) constitute anticancer drugs that, by increasing the histone acetylation level in various cell types, induce differentiation, cell cycle arrest, and apoptosis. The aim of the current review is to study the role of HDACIs in the … WebFeb 28, 2024 · Previous studies have shown that intensive macropinocytosis occurs in cancer cells and neutral red (NR) is noted for its capability to enter into the cell …
WebTo design & optimize trans-cinnamic acid loaded PLGA nanoparticles & assess its inhibitory effect on epithelial-mesenchymal transition triple-negative BC. ... the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer . Fulltext; Metrics; Get Permission; Cite this article; WebCA treatment increased the levels of lipid peroxidation in Hela and ME-180 cells. Among all the concentrations (30, 40, and 50 μg/ml) tested, 50 μg of CA showed maximum levels of thio-barbituric acid reactive substances (TBARS), CD, and LHP in HeLa and ME-180 cells (Figure 73.5).Pro-oxidant activity of hydroxycinnamic acids on DNA damage and lipid …
WebCinnamic acid containing an aryl ring with α, β-unsaturated ketone, was reported to have anticancer activity. Therefore, both chalcone and cinnamic acid have been adapted as versatile structural moieties in many cases of cancer drug development [ 30 ]. WebNov 21, 2016 · A group of compounds related to cinnamic acid (e.g., caffeic acid and ferulic acid) have been identified as potential ... CA promotes cancer cell death through alterations in mitochondrial membrane potential and lipid ... Mueller-Klieser W, Vaupel P. Lactate-induced inhibition of tumor cell proliferation. Int J Radiat Oncol Biol Phys. …
WebThe potential of cinnamic acid as an anti-inflammatory and anti-cancer agent has been studied previously. In our investigation, novel bio-isosters of cinnamyl sulfonamide hydroxamate were synthesized, characterized and confirmed for their structure and evaluated for cytotoxicity. ... -2 and -3 showed cell-growth inhibition in 6 human cancer ...
Webp-Coumaric acid (pCA) is a hydroxycinnamic acid derivative commonly found in many natural products that has been extensively studied for its anticancer activity in multiple cell lines.In this report we investigated the effects of this phytochemical as adjuvant therapy to treat glioblastoma, an infaust brain tumour characterized by the acquired or innate … grand rapids powder coatinggrand rapids press memorialsWebJul 28, 1995 · We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. The concentration causing a 50% … grand rapids press death noticesWebFeb 26, 2024 · Propolis extract or components was reported to be cytotoxic to several cancer cells [20, 21] and to induce autophagy in breast cancer cells [9].In order to elucidate whether and what kind of propolis components exhibits the above actions on prostate cancer CWR22Rv1 cells, the cytotoxic effects of eight cinnamic acid … chinese new year spy and countWebSep 9, 2024 · Results: Cinnamic acid inhibited cell viability and cell invasion, as well as decreased ECAR and OCR, in primary endometrial stromal cells. Cinnamic acid … chinese new year special foodWebCinnamic acid derivatives can be found in plant material, and they possess a remarkable variety of biological effects. ... (K562), malignant melanoma (Fem-x), and estrogen … chinese new year stamp 2022WebNov 30, 2024 · A search for naturally occurring HDAC inhibitors continues due to the adverse effects associated with known HDAC inhibitors like SAHA and TSA. Therefore … grand rapids pregnancy resource center