Fumarate lyase family

Author: onta

August undefined, 2024

WebNomenclature. This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds.The systematic name of this enzyme class is (S)-malate hydro-lyase (fumarate-forming).Other names in common use include: fumarase; L-malate hydro-lyase (S)-malate hydro-lyase; Structure WebIs fumarate Hydratase a lyase? Fumarate lyase is a substrate of the lyase class of enzymes. … 1.2 (fumarate hydratase), which catalyzes the reversible hydration of fumarate to L-malate. ... Fumarase is classified as an all alpha protein which belongs to the L-aspartase/fumarase family. It forms a tetramer of identical subunits. Crystal ...

ZFIN Gene: asl - Zebrafish Information Network

WebArgininosuccinate Lyase (ASL) Consisting of 16 exons, the ASL gene is located at position 7q11 .21, and encodes for the monomer subunit of argininosuccinate lyase. Four identical ASL monomers assemble to form a functional homotetramer of 208 kDa, which is able to breakdown argininosuccinate to yield arginine and fumarate. WebAdenylosuccinate lyase (ASL) is an enzyme that catalyzes two reactions in the de novo purine biosynthetic pathway. In both reactions it uses an E1cb elimination reaction mechanism to cleave fumarate off of the substrate. In the first reaction, ASL converts 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR) to 5-aminoimidazole-4 … graph tracks

ZFIN Gene: adsl - Zebrafish Information Network

WebFeb 7, 2024 · 5upp: Structural, biochemical and biophysical characterization of recombinant human fumarate hydratase. Skip to main content; Skip to local navigation; Skip to EBI … WebFeb 1, 2024 · This family of proteins is required for the correct synthesis and integration of Fe-S cluster in various proteins, including electron transport chain Complexes I, ... Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells. Cancer Metab., 1 (2013), p. 12, 10.1186/2049-3002-1-12. WebJan 14, 1998 · Fumarate lyase family; Argininosuccinate lyase; ... Fumarate lyase, N-terminal; L-Aspartase-like; Argininosuccinate lyase, C-terminal; Structure domain: L-aspartase/fumarase; Structure analysis Details. Assembly composition: homo tetramer . Entry contents: 1 distinct polypeptide molecule ... graph transfer learning

P9WN93 - UniProt

WebIn summary, inclusion of 2SL in the yxe locus, the opposite distribution of 2SL and yxeK, and the fumarate lyase activity of many members of the lyase class I protein family are all consistent with 2SL catalyzing the breakdown step of 2SC catabolism. ... (K c) of lyase class I family enzymes—it ensures that breakdown (i.e., fumarate release) ... Fumarase (or fumarate hydratase) is an enzyme (EC 4.2.1.2) that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs cycle and the cytosolic isoenzyme is involved in the … See more This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (S)-malate hydro-lyase (fumarate-forming). Other names in … See more Fumarase deficiency is characterized by polyhydramnios and fetal brain abnormalities. In the newborn period, findings include severe neurologic abnormalities, poor feeding, failure to thrive, and hypotonia. Fumarase deficiency is suspected in … See more • Fumarase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Structure of Fumarate • Structure of S-Malate See more Gene In humans, the FH gene is localized to the chromosomal position 1q42.3-q43. The FH gene contains 10 … See more Mechanism Figure 1 depicts the fumarase reaction mechanism. Two residues catalyze proton transfer and the … See more Click on genes, proteins and metabolites below to link to respective articles. See more • Fumarase deficiency See more graph tracking progressWebFumarate lyase, conserved site Fumarate lyase family Fumarate lyase, N-terminal L-Aspartase-like; UniProtKB:Q7SX99. InterPro 509: UniProtKB:F1QWR4. InterPro 509: Transcripts Genome Browsers. UCSC NCBI Ensembl ZFIN. Type Name Length (nt) Analysis ; mRNA: fh-201 ... graph trading

"WebFamily and domain databases. CDD. cd01359 Argininosuccinate_lyase 1 hit; Gene3D. 1.10.40.30 Fumarase/aspartase (C-terminal domain) 1 hit; ... IPR020557 Fumarate_lyase_CS; More InterPro links; PANTHER. PTHR43814 ARGININOSUCCINATE LYASE 1 hit; PTHR43814:SF1 ARGININOSUCCINATE LYASE 1 hit; PRINTS. … " - Fumarate lyase family

ZFIN Gene: asl - Zebrafish Information Network

ZFIN Gene: adsl - Zebrafish Information Network

Fumarate lyase family

Did you know?