WebMar 27, 2024 · Multiple myeloma (MM), also known as plasma cell myeloma, is a multifocal proliferation of plasma cells based in the bone marrow . It is the most common primary malignant bone neoplasm in adults. It arises from red marrow due to the monoclonal proliferation of plasma cells and manifests in a wide range of radiographic abnormalities. WebIn multiple myeloma, cancerous plasma cells (myeloma cells) are found in the bone marrow, the spongy tissue inside bones that manufactures blood cells. When myeloma cells …
Multiple Myeloma Johns Hopkins Kimmel Cancer Center
WebA low number of red blood cells, called anemia Bone damage Your bone marrow is 60% cancerous plasma cells or more. As active multiple myeloma gets worse, you'll likely feel sicker, with... WebAs myeloma cells divide and increase in number, they can affect the body in various ways. Symptoms can include: bone pain or fractures, including compression fractures of the spine, which can cause severe pain, particularly in the back. a backache that lasts for months, which can signal that multiple myeloma is affecting the bones in the spine ... da suzuki
Myeloma Guide - Leukemia & Lymphoma Society
Webnormal plasma cells. But in myeloma, a change in one plasma B cell can cause it to become a myeloma cell instead of a normal plasma cell. This mutated myeloma cell multiplies into many myeloma cells. As the myeloma cells multiply in the bone marrow, they crowd out the other types of healthy cells: red blood cells, white blood cells and platelets. WebAs the number of myeloma cells increases, fewer red blood cells, white blood cells, and platelets are made. The myeloma cells also damage and weaken the bone. Sometimes … WebMar 21, 2024 · Myomas vary in size, causing symptoms like abdominal pain and heavy menstrual bleeding though some people remain symptom-free. The cause of myomas is … da stephen a. zappala jr