Saxitoxin molecular weight
WebJan 1, 2007 · Its molecular weight was estimated to be about 400 kDa, and comprised two subunits with molecular weights of about 72 kDa and 82 kDa, respectively. A TTX-binding protein has been purified from the plasma of the puffer fish Takifugu niphobles, and its molecular weight estimated to be about 116 kDa by SDS–PAGE. WebSaxitoxin dihydrochloride C10H19Cl2N7O4 CID 132988485 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, …
Saxitoxin molecular weight
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Saxitoxin is highly toxic to guinea pigs, fatal at only 5 μg/kg when injected intramuscularly. The lethal doses (LD50) for mice are very similar with varying administration routes: i.v. is 3.4 μg/kg, i.p. is 10 μg/kg and p.o. is 263 μg/kg. The oral LD50 for humans is 5.7 μg/kg, therefore approximately 0.57 mg of saxitoxin (1/8th of a medium-sized grain of sand) is lethal if ingested and the lethal dose by injection is about one-tenth of that (approximately 0.6 μg/kg). The human inhalation toxi… WebSaxitoxin, a toxic marine natural product that targets a multitude of receptors Saxitoxin (STX) was discovered early last century and can contaminate seafood and drinking water, and over time has become an invaluable research tool and an internationally regulated chemical weapon.
WebShowing 1-3 of 3 results for "saxitoxin" within Products. Products Genes Papers Technical Documents Site Content Chromatograms. Filter & Sort. All Photos (1) ... Molecular … WebSaxitoxins are highly polar, nonvolatile, tricyclic perhydropurine alkaloids ( Figure 31.5) derived from imidazoline guanidinium ( Schantz et al., 1975 ). Various structural substitutions produce at least 57 analogues. Activity is mediated through positively charged guanidinium groups ( Wiese et al., 2012 ).
WebSaxitoxin is the parent molecule in a class of compounds, typically referred to as paralytic shellfish toxins (PSTs). Its basic structure is that of a trialkyl tetrahydropurine, with … WebJun 19, 2024 · Saxitoxin (STX), a bis-guanidinium small molecule produced by brackish and freshwater cyanobacteria and oceanic dinoflagelates associated with red tides, is one of the most lethal neurotoxins, causes paralytic shellfish poisoning (PSP), and is the only marine toxin that is declared a chemical weapon ( 1, 2 ).
WebSynonym(s): neo-Saxitoxin solution, NeoSTX. Empirical Formula (Hill Notation): C 10 H 17 N 7 O 5. CAS No.: 64296-20-4. Molecular Weight: 315.29. Compare Product No. ... Molecular Weight: 110.98. Compare Product No. Description SDS Pricing; 21049: analytical standard, 1.000 g/L Ca +2 in hydrochloric acid, traceable to BAM: Expand.
WebApr 12, 2024 · For the purposes of this work, we have assumed a molecular weight of 603.7 g/mol (i.e., nine repeated ethoxy units) per manufacturer specifications. ... Yoshikami D. Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin. J Neurophysiol. 2010;104: 88–97. pmid:20410356 . … cobb gate beach house lyme regisWebSaxitoxin (STX) is a neurotoxin having a low molecular weight (299 g/mol) that belongs to the group of PSP toxins [5, 6]. There is a significant risk to human health since STX may enter the... call failed on iphone 13 pro maxWebName and Synonym(s): Saxitoxin dihydrochloride Formula: C 10 H 19 N 7 O 4 Cl 2 Molecular weight: 372 g/mol CAS No.: 35554-08-06 Percentage in Mixture: less than or equal to 0.000001 % Name and Synonym(s): Hydrochloric acid, HCl Formula: HCl Molecular weight: 36.46 g/mol CAS No.: 7647-01-0 EC-No.: 231-595-7 Percentage in Mixture: 0.01 % call failed message on apple watchWebEvery year, the appearance of marine biotoxins causes enormous socio-economic damage worldwide. Among the major groups of biotoxins, paralytic shellfish toxins, comprising saxitoxin and its analogues (STXs), are the ones that cause the most severe effects on humans, including death. call failed when calling one numberWebJun 19, 2024 · Purified Sxph was exchanged into a buffer of 10 mM NaCl and 10 mM HEPES (pH 7.4) and then concentrated to 65 mg ml −1 using a 50-kDa molecular weight cutoff … call failed on iphone 8WebTetrodotoxin C11H17N3O8 CID 11174599 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... cobb girl vs monsterWebClinical description. Exposure to saxitoxin most commonly occurs following ingestion of certain fish that contain it in their tissues. Ingestion of saxitoxin can cause numbness of … cobb giants pitcher