Thbs1 sdc1
Thrombospondin 1, abbreviated as THBS1, is a protein that in humans is encoded by the THBS1 gene. Thrombospondin 1 is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, collagens t… WebThe F13 subtype showed a strong relationship with L1 (R = 0.871) and L5 (R = 0.928) based on Pearson correlation (Fig. 5b). In addition, the epithelial cells (L1–L5) and fibroblasts (F12) interacted with F13 through the ligand-receptor COL1A1-ITGA2B, IGF2-IGF1R/INSR, HMGB1/THBS1-SDC1, and RBP4-STRA6 (Fig. 5c).
Thbs1 sdc1
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WebSDC1: Syndecan-1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (310 aa) ... THBS1: Thrombospondin-1; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix … Web8 Mar 2024 · Abstract. We undertook a systematic study focused on the matricellular protein Thrombospondin-1 (THBS1) to uncover molecular mechanisms underlying the role of …
Web8 Mar 2024 · THBS1 is a marker of high-grade glioma. a Immunohistochemistry (IHC) of THBS1 in patient samples from grade II astrocytomas and oligodendrogliomas (upper panels), grade III anaplastic... WebThis is the first study to delineate the role of the PLAU by integrated publically available transcriptomic, proteomics, and clinical data to 1) further elucidate the mechanisms underlying...
WebTHBS1 silencing inhibits tumour cell invasion and growth, alone and in combination with anti-angiogenic therapy. Specific inhibition of the THBS1/CD47 interaction using an antagonist peptide decreases cell invasion. This is confirmed by … Web7 Nov 2024 · We demonstrate that THBS1 is an LH-stimulated, pro-angiogenic factor during the transformation of the dominant follicle into the young corpus luteum. In vivo and in …
Web15 Dec 2011 · Thrombospondin-1 (TSP-1) is an endogenous inhibitor of angiogenesis encoded by the THBS1 gene, whose promoter is activated by p53. In advanced colorectal cancers (CRC), its expression is sustained or even slightly increased despite frequent loss of …
WebMyeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state inkscape workspaceWeb18 Feb 2024 · THBS1/CD47 Modulates the Interaction of γ-Catenin With E-Cadherin and Participates in Epithelial-Mesenchymal Transformation in Lipid Nephrotoxicity … inkscape图层Web1 Mar 2024 · We subsequently confirmed that higher THBS1-SDC1 expression indicated with poor overall survival and distant metastatic free survival of TNBC patients in The … inkscape wrap text inside circleWebTHBS1 protein (human) - STRING interaction network Version: 11.5 Login Register Survey STRING STRING Search Download Help My Data Viewers Legend Settings Analysis … inkscape wrap text in shapeWeb1 May 2024 · Primary antibodies against CD9, CD63, CD81, HSP90, FGFBP1, SIPA1, THBS1, TGFBI, COL6A1, RPL10, SLC2A3 (GLUT3), MYO1D, RBP1, SMOC2, GLG1, and CEMIP (Protein-Tech Group, Rosemont, IL, USA) were used. Western blotting was performed to verify the expression of exosome marker proteins and selected exoDEPs in SW620 and SW480 … inkscape xlink hrefWeb22 May 2024 · RNA-sequencing of bone marrow-derived macrophages (BMDMs) of CD40mac-/- mice demonstrated upregulation of genes associated with alternatively activated macrophages (including Folr2, Thbs1, Sdc1 and Tns1). inkscape x yWebBackground: THBS1 (thrombospondin-1) is the extracellular matrix (ECM) protein that affects diverse cellular activities. It constitutes the tumor stroma, but the role of THBS1 in oral squamous cell carcinoma (OSCC) development is unclear. The aim of this study was to clarify the relevance of THBS1 in the pathogenesis of OSCC. inkscape youtube svg